Joint Initiative in Vaccine Economics, Phase 6: Estimating the economic burden of RSV infection and cost-effectiveness of a hypothetical RSV vaccine (JIVE 6)

Project start and end dates: 9/1/2018 - 8/31/2022

Background: 
RSV has substantial health impacts in the US, especially at the ends of the lifespan. Each year, RSV represents the most common cause of hospitalization for infants and more than 10,000 deaths are attributed to RSV in the elderly.

Objectives:
To estimate the economic burden of RSV infection and anticipated cost-effectiveness of a hypothetical RSV vaccine by:

  • Estimating the effects of RSV infection on the quality of life of patients and caregivers/family members via health utility assessment; and
  • Projecting health and economic outcomes, including cost-effectiveness, for a hypothetical RSV vaccine

Research Topics & Methods:

  • Quality of life/health utility measurement
  • Cost-effectiveness modeling
  • Family spillover

Implications:
Immunizations are among the most effective health interventions available in the US. The Centers for Disease Control and Prevention (CDC) relies on economic studies of immunization programs to guide immunization policies and practice.

Funding statement:
This project is funded as part of a larger group of studies, the Joint Initiative in Vaccine Economics (JIVE), Phase 6, through a cooperative agreement with the Centers for Disease Control and Prevention (U01IP001104), now in its 20th year of funding.

Collaborators:
Lisa Prosser, PhD
Marilyn Fisher Blanch Research Professor of Pediatrics, University of Michigan

David Hutton, PhD
Associate Professor, School of Public Health, University of Michigan

Emily Martin, PhD
Associate Professor, School of Public Health, University of Michigan

Meredith McMorrow, MD, MPH
Medical Officer, Centers for Disease Control and Prevention

Christopher Taylor, PhD
Epidemiologist, Centers for Disease Control and Prevention

Jefferson Jones, MD
Medical Officer, Centers for Disease Control and Prevention

Jamie Pike, PhD
Health Economist, Centers for Disease Control and Prevention

For more information, please contact:
Lisa Prosser, PhD, MS
Director, Susan B. Meister Child Health Evaluation and Research Center

Email: lisapros@umich.edu

Angela Rose
Project Manager

Email: angmrose@umich.edu