faculty investigators

Lisa Prosser

Lisa A. Prosser, Ph.D., M.S.

Interim Director, Child Health Evaluation and Research (CHEAR) Unit
Associate Professor, Department of Pediatrics and Communicable Diseases
Associate Professor, Department of Health Management and Policy

300 North Ingalls 6E14
Ann Arbor, Michigan 48109-5456

Office: 734-232-1077; Fax: 734-936-0941

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Administrative Support: Joyce Kennedy
Office: 734-232-0657; Fax: 734-936-0941; E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Curriculum Vitae

Biography, Education, Peer-Reviewed Publications, Programs


Dr. Prosser is an Associate Professor and Associate Director of the CHEAR Unit. Her research focuses on measuring the comparative effectiveness and cost-effectiveness of childhood health interventions using methods of decision sciences and economics. Current research topics include evaluating long-term health and economic outcomes for newborn screening programs using simulation modeling, measuring public values for screening programs, and developing new methods for valuing family spillover effects of childhood illness.

Dr. Prosser's research on the economic impact of influenza vaccination has been used in setting national vaccine policy for children and for prioritizing subgroups in vaccine shortage years. Her studies using decision science modeling to project long-term health outcomes for proposed newborn screening programs have been used to inform national newborn screening policy decisions. She is currently a member of the evidence review group for the Advisory Committee on Heritable Disorders in Newborns and Children and the ACIP Zoster Working Group.

Dr. Prosser also holds an adjunct faculty appointment at the Harvard School of Public Health.


Ph.D., Health Policy (Concentration: Decision Sciences), Harvard University, 2000
M.S., Technology & Policy, Massachusetts Institute of Technology, 1992
M.S., Management, MIT Sloan School of Management, 1992
B.A., Mathematics (Concentration: Operations Research), Cornell University, 1988

Peer-Reviewed Publications

Lavelle T, Weinstein M, Newhouse J, Munir K, Kuhlthau K, Prosser LA.
Economic burden of childhood autism spectrum disorders.
J Pediatr. 2014. In press.

Wright D, Taveras E, Gillman M, Horan C, Hohman K, Gortmaker S, Prosser LA.
The cost of a primary care-based childhood obesity prevention intervention.
BMC Health Services Research. 2014. In press.

Wright D, Prosser LA.
The impact of overweight and obesity on pediatric medical expenditures.
Appl Health Econ Health Policy. 2014. In press.

Sharp A, Prosser LA, Walton M, Blow F, Chermack S, Zimmerman M, Cunningham R.
Cost analysis of youth violence prevention.
J Pediatr. 2013. In press.

Damiano DL, Prosser LA, Curatalo LA, Alter KE.
Muscle plasticity and ankle control after repetitive use of a functional electrical stimulation device for foot drop in cerebral palsy.
Neurorehabilitation and neural repair. Mar-Apr 2013;27(3):200-207.




Zickafoose JS, DeCamp LR, Sambuco DJ, Prosser LA.
Parents' preferences for enhanced access to the pediatric medical home: a qualitative study.
The Journal of ambulatory care management. Jan-Mar 2013;36(1):2-12.

Prosser LA, Payne K, Rusinak D, Shi P, Messonnier M.
Using a discrete choice experiment to elicit time trade-off and willingness-to-pay amounts for influenza health-related quality of life at different ages.
PharmacoEconomics. Apr 2013;31(4):305-315.

Wittenberg E, Prosser LA.
Disutility of illness for caregivers and families: a systematic review of the literature. PharmacoEconomics.
PharmacoEconomics. Jun 2013;31(6):489-500.

Vandorsten J, Dodson W, Espeland M, Grobman W, Guise J, Mercer B, Minkoff H, Poindexter B, Prosser LA, Sawaya G, Scott J, Silver R, Smith L, Thomas A, Tita A.
NIH consensus development conference: diagnosing gestational diabetes mellitus.
NIH consensus and state-of-the-science statements. Mar 4-6 2013;29(1):1-31.

Ungar WJ, Prosser LA, Burnett HF.
Values and evidence colliding: health technology assessment in child health.
Expert review of pharmacoeconomics & outcomes research. Aug 2013;13(4):417-419.

Wittenberg E, Saada A, Prosser LA.
How illness affects family members: a qualitative interview survey.
The patient. Dec 2013;6(4):257-268.

Chang J, Freed G, Prosser LA, Patel I, Eriskson S, Bagozzi R, Balkrishnan R.
Comparisons of health care utilization outcomes in children with asthma enrolled in private insurance plans versus Medicaid.
J Pediatri Health Care. Jan-Feb 2014;28(1):71-79.

Prosser LA, Payne K, Rusinak D, Shi P, Messonnier M.
Using a discrete choice experiment to elicit time trade-off and willingness-to-pay amounts for influenza health-related quality of life at different ages.
PharmacoEconomics. Apr 2013;31(4):305-315.

Kemper AR, Green NS, Calonge N, Lam WK, Comeau AM, Goldenberg AJ, Ojodu J, Prosser LA, Tanksley S, Bocchini Jr JA.
Decision-making process for conditions nominated to the Recommended Uniform Screening Panel: statement of the US Department of Health and Human Services Secretary's Advisory Committee on Heritable Disorders in Newborns and Children.
Genetics in medicine: official journal of the American College of Medical Genetics. Aug 1 2013.

Zickafoose JS, Decamp LR, Prosser LA.
Association between enhanced access services in pediatric primary care and utilization of emergency departments: a national parent survey.
The Journal of pediatrics. Nov 2013;163(5):1389-1395 e1381-1386.

Vandorsten JP, Dodson WC, Espeland MA, Grobman WA, Guise JM, Mercer BM, Minkoff HL, Poindexter B, Prosser LA, Sawaya GF, Scott JR, Silver RM, Smith L, Thomas A, Tita AT.
NIH consensus development conference: diagnosing gestational diabetes mellitus.
NIH Consens State Sci Statements. 2013;29(1):1-31.

Wittenberg E, Ritter G, Prosser LA.
Evidence of spillover of illness among household members: EQ-5D scores from a US sample.
Med Decis Making. Feb 2013;33(2):235-243.

Chang J, Freed G, Prosser LA, Patel I, Erickson S, Bagozzi R, Balkrishnan R.
Associations between physician financial incentives and prescribing of anti‐Asthmatic medications in children in US outpatient settings.
Journal of Child Health. Jun 2013;17(2):125-137.

Song JW, Chung KC, Prosser LA.
Ulnar neuropathy at the elbow: A cost-utility analysis.
J Hand Surg. 2012;37(8):1617-1629.e3.

Prosser LA.
Comparative effectiveness and child health.
PharmacoEconomics. 2012; 30(8):637-45.

Prosser LA, Grosse SD, Kemper AR, Tarini BA, Perrin JM.
Decision analysis, economic evaluation, and newborn screening: Challenges and opportunities.
Genetics in medicine: official journal of the American College of Medical Genetics. Apr 5 2012. 

Gidengil C, Lieu TA, Payne K, Rusinak D, Messonnier M, Prosser LA.
Parental and societal values for the risks and benefits of childhood combination vaccines.
Vaccine. 2012;30(23):3445-52.

Dempsey AF, Pangborn HM, Prosser LA.
Cost-effectiveness of routine vaccination of adolescent females against cytomegalovirus vaccine.
Vaccine. 2012;30(27):4060-6.

Rhodes ET, Goran MI, Lieu TA, Lustig RH, Prosser LA, Songer TJ, Weigensberg MJ, Weinstock RS, Gonzalez T, Rawluk K, Zoghbi RM, Ludwig DS, Laffel LM.
Health-related quality of life in adolescents with or at risk for Type 2 diabetes mellitus.
J Pediatr. 2012;160(6):911-7.

Kimmel AD, Daniels N, Betancourt TS, Wood R, Prosser LA.
Decision maker priorities for providing antiretroviral therapy in HIV-infected South Africans: a qualitative assessment.
AIDS Care. 2012;24(6):778-92.

Rhodes ET, Prosser LA, Hoerger TJ, Lieu T, Ludwig DS, Laffel LM.
Estimated morbidity and mortality in adolescents and young adults diagnosed with Type 2 diabetes mellitus.
Diab Med. 2012;29(4):453-63.

Prosser LA, Grosse SD, Wittenberg E.
Health utility elicitation: Is there still a role for direct methods?
PharmacoEconomics. 2012; Feb 1; 30(2):83-6.

Lavelle TA, Uyeki TM, Prosser LA.
Cost-effectiveness of oseltamivir treatment for children with uncomplicated seasonal influenza.
J Pediatr. 2012;160(1):67-73

Gatwood J, Meltzer MI, Messonnier M, Ortega-Sanchez IR, Balkrishnan R, Prosser LA.
Seasonal influenza vaccination of healthy, working-age adults: A review of economic evaluations.
Drugs. 2012 Jan 1;72(1):35-48.

Lavelle TA, Meltzer MI, Gebremariam A, Lamarand K, Fiore AE, Prosser LA.
Community-based values for 2009 pandemic influenza A (H1N1) illnesses and vaccination-related adverse events.
PLoS ONE. 6(12):e27777.doi:10.1371/journal.pone.0027777

Prosser LA, Lavelle TA, Fiore AE, Bridges CB, Reed C, Jain S, Dunham KM, Meltzer MI.
Cost-effectiveness of 2009 Pandemic Influenza A(H1N1) Vaccination in the United States.
PLoS ONE. 2011;6(7):e22308. Epub 2011 Jul 29.

Rhodes ET, Prosser LA, Lieu TA, Songer TJ, Ludwig DS, Laffel LM.
Preferences for type 2 diabetes health states among adolescents with or at risk of type 2 diabetes mellitus.
Pediatric Diabetes. 2011 Apr 13. doi: 10.1111/j.1399-5448.2011.00772.x. [Epub ahead of print]

Taveras EM, Gortmaker SL, Hohman KH, Horan CM, Kleinman KP, Mitchell K, Price S, Prosser LA, Rifas-Shiman SL, Gillman MW.
Randomized controlled trial to improve primary care to prevent and manage childhood obesity: the High Five for Kids study.
Arch Pediatr Adolesc Med. 2011 Aug;165(8):714-22. Epub 2011 Apr 4.

Wittenberg E, Prosser LA.
Ordering errors, objections and invariance in utility survey responses: a framework for understanding who, why and what to do.
Appl Health Econ Health Policy. 2011;9(4):225-41.

Eisenberg D, Freed GL, Davis MM, Singer D, Prosser LA.
Valuing health at different ages: evidence from a nationally representative survey in the United States.
Appl Health Econ Health Policy. 2011;9(3):149-56.

Bridges JFP, Hauber AB, Marshall D, Lloyd A, Prosser LA, Regier DA, Johnson FR, Mauskopf J.
Conjoint Analysis Applications in Health - a Checklist: Report of the ISPOR Conjoint Analysis Good Research Practices Task Force.
Value Health. 2011;14(4):403-13.

Prosser LA, Melzer MI, Fiore A, Epperson S, Bridges CB, Hinrichsen V, Lieu TA.
Effects of adverse events on the projected population benefits and cost-effectiveness of using live attenuated influenza vaccine in children aged 6 months to 4 years.
Arch Pediatr Adolesc Med. 2011;165(2):112-8.

Belfort M, Zupancic J, Riera K, Turner J, Prosser LA.
Health state preferences associated with weight status in children and adolescents.
BMC Pediatrics. 2011:11(1):12.

Wang YC, Cheung AM, Bibbins-Domingo K, Prosser LA, Cook NR, Goldman L, Gillman MW.
Effectiveness and cost-effectiveness of blood pressure screening in adolescents in the United States.
J Pediatr. 2011;158(2):257-64.

Prosser LA, Rusinak D, Payne K, Uyeki T, Kamimoto L, Messonnier M.
Valuing health across the lifespan: health state preferences for seasonal influenza illnesses in patients of different ages.
Value Health. 2011;14(1):135-43.

Perrin JM, Knapp AA, Browning MF, Comeau AM, Green NS, Lipstein EA, Metterville DR, Prosser LA, Queally D, Kemper AR.
An evidence development process for newborn screening.
Genet Med. 2010;12(3):131-134.

Grosse SD, Prosser LA, Asakawa K, Feeny D.
QALY weights for neurosensory impairments in pediatric economic evaluations: Case studies and a critique.
Expert Review of Pharmacoeconomics & Outcomes Research. 2010;10(3): 293-308.

McBrien K, Abrams A, Kleinman K, Prosser LA.
Use of outcomes-weighted ROC curves to evaluate surveillance systems for bioterrorist attacks.
BMC Med Inform Decis Mak. 2010;10:1-11.

Lipstein EA, Vorono S, Browning MF, Green NS, Kemper AR, Knapp AA, Prosser LA, Perrin JM.
A systematic review of the evidence for newborn screening and treatment of severe combined immunodeficiency.
Pediatrics. 2010;125(5):e1226-35.

Prosser LA, Kong CY, Rusinak D, Waisbren SE.
Projected costs, risks, and benefits of expanded newborn screening for MCADD.
Pediatrics. 2010;125(2):e286-294.

Sonneville KR, La Pelle N, Taveras EM, Gillman MW, Prosser LA.
Economic and other barriers to adopting recommendations to prevent childhood obesity: results of a focus group study with parents.
BMC Pediatrics. 2009;9(81):1-21.

Lieu TA, Ray GT, Ortega-Sanchez IR, Kleinman K, Rusinak D, Prosser LA.
Willingness-to-pay for a quality-adjusted life-year based on community member and patient preferences for temporary health states associated with zoster.
PharmacoEconomics. 2009; 27(12): 1005-16.

Lipstein EA, Perrin JM, Waisbren SE, Prosser LA.
Impact of false-positive newborn metabolic screening results on early health care utilization.
Genet Med. 2009; 11(10):1-6.

Wright DR, Wittenberg E, Swan JS, Miksad RA, Prosser LA.
Methods for measuring temporary health states for cost-utility analyses (review).
PharmacoEconomics. 2009; 27(9): 713-23.

Prosser LA.
Current challenges and future research in measuring preferences for pediatric health outcomes (invited editorial).
J Pediatr. 2009;155(1):7-9.

O'Brien MA, Prosser LA, Paradise JL, Ray GT, Kulldorff M, Kurs-Lasky M, Hinrichsen V, Mehta J, Colborne JK, Lieu TA.
New vaccines against otitis media: projected benefits and cost-effectiveness.
Pediatrics. 2009;123(6):1452-1463.

Prosser LA, Ladapo JA, Rusinak D, Waisbren SE.
Parental tolerance for false-positive newborn screening results.
Arch Pediatr Adolesc Med. 2008;162(9):870-6.

Lieu TA, Ortega-Sanchez I, Ray GT, Rusinak D, Yih WK, Choo PW, Shui I, Kleinman K, Harpaz R, Prosser LA.
Community and patient values for preventing zoster.
PharmacoEconomics. 2008;26(3):235-49.

Ortega-Sanchez IR, Lee GM, Jacobs RJ, Prosser LA, Molinari NA, Zhang X, Baine WB, McCauley MM, Miller T.
Projected cost-effectiveness of new vaccines for adolescents in the United States (review).
Pediatrics.2008;121 Suppl 1:S63-78.

Prosser LA, O’Brien MA, Molinari NA, Hohman KH, Nichol KL, Wortley PM, Messonnier ML, Lieu TA.
Non-traditional settings for influenza vaccination of adults: Costs and cost-effectiveness.
PharmacoEconomics. 2008;26(2):163-178.

Ladapo JA, Neumann PJ, Keren R, Prosser LA.
Valuing children’s health: a comparison of cost-utility analyses for adult and pediatric health interventions (review).
PharmacoEconomics. 2007;25(10):817-828.

Prosser LA, Hammitt JK, Keren R.
Measuring health preferences for use in cost-utility and benefit analyses of interventions in children: Theoretical and methodological considerations.
PharmacoEconomics. 2007;25(9):713-726.

Prosser LA, Wittenberg E.
Do risk attitudes differ across domains and respondent types?
Med Decis Making. 2007;27(3):281-287.

Simon SR, Rodriguez HP, Majumdar SR, Kleinman K, Warner C, Salem-Schatz S, Miroshnik I, Soumerai SB, Prosser LA.
Economic analysis of a randomized trial of academic detailing interventions to improve use of antihypertensive medications.
J Clin Hyper. 2007;9(1):15-20.

Prosser LA, Corso PS.
Measuring health-related quality of life for child maltreatment: A systematic literature review.
Health Qual Life Outcomes. 2007;5(1)1-17. Available at: http://www.hqlo.com/content/5/1/42.

Eisenberg DM, Post DE, Davis RB, Connelly MT, Legedza AT, Hrbek AL, Prosser LA, Buring JE, Cherkin DC.
Addition of choice of complementary therapies to usual care for acute low back pain: a randomized controlled trial.
Spine. 2007;32(2):151-8.

Prosser LA, Bridges CB, Uyeki TM, Hinrichsen VL, Meltzer MI, Molinari NA, Schwartz B, Thompson WW, Fukuda K, Lieu TA.
Health benefits, risks, and cost-effectiveness of influenza vaccination of children.
Emerg Infect Dis. 2006;12(10):1548-1558.

Skelding PC, Majumdar SR, Kleinman K, Warner C, Salem-Schatz S, Miroshnik I, Prosser LA, Simon SR.
Clinical and non-clinical correlates of adherence to prescribing guidelines for hypertension in a large managed care organization.
J Clin Hypertension. 2006;8(6):414-419.

Wittenberg E, Halpern E, Divi N, Prosser LA, Araki SS, Weeks JC.
The effect of age, race and gender on preference scores for hypothetical health states.
Qual Life Res. 2006;15(4):645-653.

Gupta RS, Bewtra M, Prosser LA, Finkelstein JA.
Predictors of hospital charges for children admitted with asthma.
Ambul Pediatr. 2006;6(1):15-20.

Simon SR, Majumdar SR, Prosser LA, Salem-Schatz S, Warner C, Kleinman K, Miroshnik I, Soumerai SB.
Group versus individual academic detailing to improve the use of antihypertensive medications in primary care: a cluster-randomized controlled trial.
Am J Med. 2005;118(5):521-528.

Prosser LA, Bridges CB, Uyeki TM, Rego VH, Ray GT, Meltzer MI, Schwartz B, Thompson WW, Fukuda K, Lieu TA.
Values for preventing influenza-related morbidity and vaccine adverse events in children.
Health Qual Life Outcomes. 2005;3(18):1-16.

Prosser LA, Kuntz KM, Bar-Or A, Weinstein MC.
Cost-effectiveness of interferon beta-1a, interferon beta-1b, and glatiramer acetate in newly diagnosed non-primary progressive multiple sclerosis.
Value Health. 2004;7(5):554-568.

Prosser LA, Lieu TA.
Comments on the Prosser et al approach to value disease reduction in children: In reply (letter).
Pediatrics. 2004;114:1375-1376.

Prosser LA, Ray GT, O'Brien M, Kleinman K, Santoli J, Lieu TA.
Preferences and willingness to pay for health states prevented by pneumococcal conjugate vaccine.
Pediatrics. 2004;113(2):283-290.

Wang SJ, Middleton B, Prosser LA, Bardon CG, Spurr CD, Carchidi PJ, Kittler AF, Goldszer RC, Fairchild DG, Sussman AJ, Kuperman GJ, Bates DW.
A cost-benefit analysis of electronic medical records in primary care.
Am J Med. 2003;114(5):397-403.

Prosser LA, Kuntz KM, Bar-Or A, Weinstein MC.
Patient and community preferences for treatments and health states in multiple sclerosis.
Mult Scler. 2003;9:311-319.

Lieu TA, Thompson KM, Prosser LA, O’Brien MA, Yusuf HR, Shefer AM, Weinstein MC, Rickert DL.
Emerging issues in vaccine economics: perspectives from the USA.
Expert Rev Vaccines. 2002:1(4):433-442.

Prosser LA, Kuntz KM, Bar-Or A, Weinstein MC.
The relationship between risk attitude and treatment choice in patients with relapsing-remitting multiple sclerosis.
Med Decis Making. 2002;22:506-513.

Prosser LA, Stinnett AA, Goldman L, Weinstein MC.
Cost-effectiveness analyses (letter).
Ann Intern Med 2001;135(5):383.

Prosser LA, Stinnett AA, Goldman PA, Williams LW, Hunink MG, Goldman L, Weinstein MC.
Cost-effectiveness of cholesterol-lowering therapies according to selected patient characteristics.
Ann Intern Med. 2000;132(10):768-779.

Prosser LA, Koplan JP, Neumann PJ, Weinstein MC.
Barriers to using cost-effectiveness analysis in managed care decision making.
Am J Manag Care. 2000;6(2):173-179.



Program in Comparative Effectiveness and Child Health
Working Group on Modeling Health and Economic Outcomes